| 產(chǎn)品編號(hào) | bs-6118R |
| 英文名稱 | VILIP1 Rabbit pAb |
| 中文名稱 | 神經(jīng)視錐蛋白樣1(神經(jīng)鈣蛋白)抗體 |
| 別 名 | VISL1_HUMAN; Visinin-like protein 1; Visinin like protein 1; Hippocalcin-like protein 3; visinin-like protein 1 isoform 3; Neurocalcin alpha; HLP3; HLP 3; HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1; VLP-1; VISL 1; VSNL1. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 Alzheimer's |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Chicken) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VILIP1: 121-191/191 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008] Function: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. Tissue Specificity: Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level). Similarity: Belongs to the recoverin family. Contains 4 EF-hand domains. SWISS: P62760 Gene ID: 7447 Database links: Entrez Gene: 396189 Chicken Entrez Gene: 7447 Human Entrez Gene: 26950 Mouse Omim: 600817 Human SwissProt: P62764 Chicken SwissProt: P62760 Human SwissProt: P62761 Mouse Unigene: 444212 Human Unigene: 27005 Mouse Unigene: 105934 Rat |
| 產(chǎn)品圖片 |
Sample: Recombinant human VILIP1 protein at 100 ng
Primary: Anti-VILIP1 (bs-6118R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 20 kD
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