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Human TNF-α ELISA Kit (bsk11014)  
訂購熱線：400-901-9800
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訂購QQ：  400-901-9800
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96T/2900.00元
大包裝/詢價
產品編號 bsk11014
英文名稱 Human TNF-α ELISA Kit
中文名稱 人腫瘤壞死因子α酶聯(lián)免疫試劑盒
別    名 TNF-alpha; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF-a; TNF alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfa  
Specific References  (10)     |     bsk11014 has been referenced in 10 publications.
[IF=20.693] Hanlin He. et al. ADAM9: A regulator between HCMV infection and function of smooth muscle cells. J MED VIROL. 2022 Nov;:  ELISA ;  Human.  
[IF=12.479] Qi Chen. et al. Ruthenium complexes boost NK cell immunotherapy via sensitizing triple-negative breast cancer and shaping immuno-microenvironment. Biomaterials. 2022 Jan;:121371  ELISA ;  Human.  
[IF=8.079] Qiu, Zhenhua. et al. Human umbilical cord mesenchymal stem cell-derived exosomal miR-335-5p attenuates the inflammation and tubular epithelial–myofibroblast transdifferentiation of renal tubular epithelial cells by reducing ADAM19 protein levels. STEM CELL RES THER. 2022 Dec;13(1):1-15  WB ;  Human.  
[IF=5.999] Cheng Chen. et al. Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization. COLLOID SURFACE B. 2023 Feb;222:113086  ELISA ;  Human.  
[IF=4.964] Qing Zhu. et al. Soluble Vascular Cell Adhesion Molecule-1 as an Inflammation-Related Biomarker of Coronary Slow Flow. J CLIN MED. 2023 Jan;12(2):543  ELISA ;  Human.  
[IF=4.545] Feng Li. et al. Eriobotrya japonica leaf triterpenoid acids ameliorate metabolic syndrome in C57BL/6J mice fed with high-fat diet. Biomed Pharmacother. 2020 Dec;132:110866  ELISA ;  
[IF=3.269] Meizhu Chen. et al. Helicobacter pylori promotes inflammatory factor secretion and lung injury through VacA exotoxin-mediated activation of NF-κB signaling. BIOENGINEERED. 2022;13(5):12760-12771  ELISA ;  Human.  
[IF=2.836] Dai Jiangwen. et al. Liver kinase B1 attenuates liver ischemia/reperfusion injury via inhibiting the NLRP3 inflammasome. Acta Bioch Bioph Sin. 2021 Mar;:  ELISA ;  Mouse.  
[IF=2.493] Rifeng Chen. et al. Overexpression of CD86 enhances the ability of THP-1 macrophages to defend against Talaromyces marneffei. IMMUN INFLAMM DIS. 2022 Nov;10(12):e740  ELISA ;  Human.  
[IF=2.293] Qiu M et al. Effects of miR-150-5p on the growth and SOCS1 expression of rheumatoid arthritis synovial fibroblasts. Clin Rheumatol. 2019 Dec 26.  ELISA ;  Human.  
種    屬 Human
線性范圍 15.60 - 1,000 pg/mL
應用范圍 S/P/CC
檢測限 7 pg/mL
適用樣品基質 cell culture supernates, serum, and plasma.
保存條件 Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.).
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide stimulated macrophages, and causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.

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