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phospho-AMPK alpha-2 (Thr172), PerCP conjugated (bs-4002R-PerCP)  
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100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4002R-PerCP
英文名稱 phospho-AMPK alpha-2 (Thr172), PerCP conjugated
中文名稱 PerCP標記的磷酸化腺苷單磷酸活化蛋白激酶α2抗體
別    名 AMPK alpha 1 (phospho T183) + AMPK alpha 2 (phospho T172); PRKAA1(phospho T172); AMPK alpha 1 + AMPK alpha 2 (phospho T172); phospho-AMPK alpha-1 (Thr183); 5'-AMP-activated protein kinase catalytic subunit alpha-2; AAPK2_HUMAN; AAPK1_HUMAN; ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK alpha 2 chain; AMPK subunit alpha-2; AMPK2; AMPK 2; AMPKa2; AMPK a2; AMPK-a2 AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2; Protein kinase AMP activated alpha 2 catalytic subunit; Protein kinase AMP activated catalytic subunit alpha 2.  
研究領域 免疫學  神經(jīng)生物學  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  糖尿病  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 64kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Thr172: LR(p-T)SC 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

SWISS:
P54646

Gene ID:
5563

Database links:

Entrez Gene: 5563 Human

Entrez Gene: 108079 Mouse

Entrez Gene: 78975 Rat

Omim: 600497 Human

SwissProt: P54646 Human

SwissProt: Q8BRK8 Mouse

SwissProt: Q09137 Rat

Unigene: 437039 Human

Unigene: 48638 Mouse

Unigene: 64583 Rat



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